The use Talliton during pregnancy and during breast-feeding newborns contraindicated. If necessary, use during lactation should be excluded trenbolone hex breastfeeding.
Dosing and Administration
The tablets taken orally. Should be swallowed whole and drink plenty of fluids. When essentsialnoy hypertension : The recommended starting once a day for 2 days (one tablet of 12.5 mg in the morning and one tablet of 6.25 mg twice daily – one morning and one evening). The recommended maintenance dose is 25 mg Talliton (one tablet of 25 mg in the morning and one tablet of 12.5 mg twice a day – one in the morning and the other -vecherom). In the case of an unsatisfactory trenbolone hex result, but not earlier than 14 days of treatment, the dose can be increased to a maximum – 50 mg per day (one tablet of 25 mg twice a day – morning and evening). The maximum single dose of 25 mg, and the daily dose should not exceed 50 mg. Chronic stable angina pectoris : The recommended initial dose – 12.5 mg twice a day (morning and evening) during the first two days. The recommended maintenance dose – 25 mg twice a day (morning and evening). In the case of unsatisfactory results, but not earlier than 14 days of treatment, the dose can be increased to a maximum – 50 mg twice daily (two tablets of 25 mg in the morning and two tablets in the evening). Congestive heart failure : the dose should be adjusted individually, while increasing carry out a thorough dose monitoring.
The dose is selected based on each individual case. It is necessary to observe the condition of the patient within 2-3 hours after the first or after receiving the first dose is increased. Additional application requires a stable clinical condition. Dose and administration of other drugs, such as digoxin, diuretics and inhibitors, must be recorded to the destination. Patients must take the tablets during the meal (to reduce the risk of orthostatic hypotension) The recommended starting dose of 3,125 mg twice a day for 14 days (½ tablets of 6.25 mg in the morning and evening). If the patient tolerated the treatment well and there is a need to increase the dose can be 6.25 mg twice a day (one tablet of 6.25 mg in the morning and one -vecherom). Possible subsequent increase in the dose of 12.5 mg twice a day (one tablet of 12.5 mg in the morning and evening), then up to 25 mg twice a day (one tablet of 25 mg in the morning and evening). Patients administered the maximum tolerated dose. The maximum recommended dose – 25 mg twice a day (one tablet of 25 mg in the morning and one – in the evening) for patients weighing up to 85 kg and 50 mg twice daily (two tablets of 25 mg in the morning and two in the evening) for patients weighing more than 85 kg. Patients with heart failure to prevent orthostatic hypotension it is recommended to take the drug during meals. At the beginning of the treatment and to increase each dose condition of patients should be monitored as possible worsening of heart failure. May develop fluid retention, and due to the vasodilator trenbolone hex and lethargy. When fluid retention should increase the dose of diuretics, in addition, may require temporary dose reduction Talliton. In some cases, treatment should be temporarily suspend Talliton.
At recommended doses, the drug is generally well tolerated, but in some cases may cause side effects: On the part of the central nervous system : headache, syncope, dizziness, fatigue, rarely – depressed mood, sleep disturbance, paresthesia Cardio-vascular system : orthostatic hypotension, bradycardia, marked reduction in blood pressure, angina, rarely – a violation of the peripheral circulation (cold extremities), “intermittent” claudication or Raynaud’s syndrome, peripheral edema, atrioventricular block, the progression of heart failure of the respiratory system : dyspnea, bronchospasm. seldom – nasal congestion From the gastrointestinal tract : dry mouth, nausea, diarrhea, abdominal pain. rarely – constipation, vomiting, increased activity of “liver” transaminases. On the part of the skin : allergic rash, hives, itching, worsening of trenbolone hex psoriatic lesions, it is very rare – anaphylactoid reactions From the blood : leukopenia, thrombocytopenia. Other : rarely – pain in the extremities, a decrease production of tear fluid, eye irritation, urinary disorders, renal failure, influenza-like syndrome. As with other beta-blockers may occur latently current diabetes or worsen its symptoms.
Overdose Symptoms : may develop severe hypotension, bradycardia, heart failure, cardiogenic shock, cardiac arrest. Treatment : success can be gastric lavage or administration of emetics, if they are carried out within a few hours after taking the drug. Overdose trenbolone hex requires intensive treatment. The patient should be in the raised position. Antidote beta-adrenoceptor blocking action is ortsiprenalin or isoprenaline 0.5-1 mg intravenously and / or glucagon in a dose of 1-5 mg (maximum dose 10 mg). Severe hypotension treated with parenteral fluids and repeated administration of epinephrine in a dose of 5-10 mg (or intravenous infusion at a rate of 5 g / min). For the treatment of excessive bradycardia atropine administered intravenously at a dose of 0,5-2 mg. In order to maintain cardiac function: Glucagon – 1-10 mg intravenously quickly for 30 seconds, after which a constant infusion rate of 2-5 mg / hour. If the predominant peripheral vasodilator effect (warm extremities, in addition to significant hypotension), you must assign norepinephrine in repeated doses for 5-10 mg, or in the form of infusion -. 5 g / min for the relief of bronchospasm prescribe beta-agonists (as aerosol or intravenously) or aminophylline intravenously. If you develop seizures, it is recommended the slow introduction of diazepam or clonazepam. In severe cases of intoxication when dominated shock symptoms antidote treatment should continue until the patient’s condition has stabilized, considering the half-life of carvedilol (6-10 hours).