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  • tren hexahydrobenzylcarbonate

    Rare increased heart rate, decreased blood pressure. Very rare (shock-like) vascular collapse. In some cases: lengthening of the tren hexahydrobenzylcarbonate interval.The action on the muscles, tendons and bones. Rare: defeat tendons (including tendonitis), joint and muscle pain
    Very rare: tendon rupture (eg Achilles tendon); this side effect may occur within 48 hours after the start of treatment and may be bilateral in nature (see “Cautions.”); muscle weakness, which is of particular importance for patients suffering from myasthenia gravis.
    In some cases: muscle damage (rhabdomyolysis).Effects on the liver and kidneysOften: increased activity of liver enzymes (eg, alanine aminotransferase and aspartate aminotransferase).
    Rare: increased bilirubin and serum creatinine (sign of limitation of liver or kidney function).
    Very rare: hepatic reactions (eg, inflammation of the liver); deterioration of renal function until the acute renal failure, for example, due to allergic reactions (interstitial nephritis).Haematic. Sometimes: increase in the number of eosinophils, a decrease in the number of white blood cells
    Rare: neutropenia; thrombocytopenia, which may be accompanied by increased bleeding.
    Very rare: agranulocytosis and the development of severe infections (persistent or recurrent fever, sore throat and a persistent deterioration of health).
    In some cases: haemolytic anemia; pancytopenia.Other side effectsSometimes:. General weakness (asthenia)
    Very rarely. Fever, allergic pneumonitis
    Any antibiotic therapy can cause changes in the microflora (bacteria and fungi), which is normally present in humans. For this reason, it may happen enhanced reproduction of bacteria and fungi that are resistant to antibiotics are used (secondary infection  tren hexahydrobenzylcarbonate and superinfection), which in rare cases may require additional treatment.

    Overdose

    The most important expected symptoms (signs) of erroneous overdosing tavanic occur at the level of the central nervous system (confusion, dizziness, impairment of consciousness and seizures seizures by type epipripadkov). In addition, it can be marked gastrointestinal symptoms (eg, nausea) and erosive lesions of the mucous membranes.
    The clinical and pharmacological studies conducted by the supra-therapeutic doses of levofloxacin was shown lengthening the  interval.
    Treatment should be focused on presenting symptoms. Levofloxacin is not displayed by dialysis (hemodialysis, peritoneal dialysis and continuous peritoneal dialysis). Specific antidote (counteracting agent) does not exist. Error receiving one extra  of the drug will have no harmful effects.

    Interaction with other drugs

    There are reports of pronounced lowering the threshold of convulsive readiness, while the use of quinolones and substances that can, in turn, lower the cerebral seizure threshold. Equally, it also relates to the simultaneous use of quinolones and theophylline, fenbufena tren hexahydrobenzylcarbonate or similar to it nonsteroidal antiinflammatory drugs (for the treatment of rheumatic diseases).
    The drug tavanic expression weakened, while the use of sucralfate (means to protect the gastric mucosa). The same thing happens with the simultaneous use of magnesium-aluminum containing antacids or (drugs for the treatment of heartburn and gastralgia), as well as salts of iron (for the treatment of anemia). Tavanic should take no less than 2 hours before or 2 hours after the administration of these agents.With calcium carbonate interaction have been identified. Receiving corticosteroids increase the risk of tendon rupture.
    With the simultaneous use of vitamin K antagonists should be monitored for blood coagulation system.
    Excretion (renal clearance) of levofloxacin slightly slowed down by the action of cimetidine and probenicid. It should be noted that this interaction is almost does not have any clinical significance. However, while the use of drugs such as cimetidine and probenicid blocking certain way of deducing (tubular secretion), treatment with levofloxacin should be performed with caution. This applies primarily to patients with reduced renal function.
    Levofloxacin slightly increases the tren hexahydrobenzylcarbonate of cyclosporin.
    Receiving corticosteroids increase the risk of tendon rupture.

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  • parabolan

    With caution the drug should be used in elderly patients due to the high probability of the presence of a concomitant decrease in renal function (deficiency of glucose-6-phosphate dehydrogenase).

    Tavanic tablets parabolan taken orally one or two times a day. Doses are determined by the nature and severity of the infection and the sensitivity of the alleged pathogen. It is necessary to strictly adhere to the instructions for use, as otherwise Tavanic can cause an inadequate effect. Patients with normal or moderately decreased kidney function (creatinine clearance> 50 mL / min.) Can recommend the following dosing regimen of the drug:

    • sinusitis (inflammation of the sinuses): 2 tablets Tavanic 250 mg or 1 tablet Tavanic 500 mg 1 time per day (or 500 mg levofloxacin) – 10-14 days;
    • exacerbation of chronic bronchitis: 1 tablet Tavanic 250 mg 1 time per day (or 250 mg levofloxacin) or 2 tablets of Tavanic 250 mg or 1 tablet Tavanic 500 mg 1 time per day (or 500 mg levofloxacin) – 7-10 days;
    • community-acquired pneumonia: 2 tablets Tavanic 250 mg or 1 tablet Tavanic 500 mg 1-2 times a day (or 500-1000 mg levofloxacin) – 7-14 days;
    • uncomplicated urinary tract infections: 1 tablet Tavanic 250 mg 1 time per day (or 250 mg levofloxacin) -3 days;
    • Prostatitis: 2 tablets Tavanic 250 mg or 1 tablet Tavanic 500 mg – 1 per day (or 500 mg levofloxacin) 28 days.
    • complicated urinary tract infections, including pyelonephritis: 1 tablet Tavanic 250 mg 1 time per day (or 250 mg levofloxacin) 7-10 days;
    • Skin and soft tissue infections: 1 tablet Tavanic 250 mg 1 time per day (or 250 mg levofloxacin) or 2 tablets of Tavanic 250 mg or 1 tablet Tavanic 500 mg 1-2 times a day (or 500-1000 mg of levofloxacin) 7-14 days;
    • sentitsemiya / bacteremia: 2 tablets Tavanic 250 mg or 1 tablet Tavanic 500 mg 1-2 times a day (or 500-1000 mg levofloxacin) – 10-14 days;
    • Intra-abdominal infections: 2 tablets Tavanic 250 mg or 1 tablet Tavanic 500 mg 1 time per day (or 500 mg levofloxacin) 7-14 days (in combination with antibacterial drugs acting on the anaerobic flora);
    • comprehensive treatment of drug-resistant forms of TB: 1-2 tablets Tavanic 500 mg 1-2 times a day (500-1000 mg of levofloxacin, respectively) up to 3 months;

    Levofloxacin is excreted parabolan mainly by the kidney, so the treatment of patients with renal impairment function is required to reduce the dose of the drug. The relevant information on this matter is contained in the following table:

    In sharp dispensing
    tablets should be taken without chewing and drinking plenty of fluids (0.5 to 1 cup).In the selection of dose tablets can be broken along the separation groove.The drug can be taken before meals or at any time between meals (see. “Interactions” section).

    Dermal hypersensitivity reactions and overall reaction
    Sometimes the itching and redness of the skin.
    Rare: general reactions of hypersensitivity (anaphylactic and anaphylactoid reaction) with symptoms such as urticaria, bronchoconstriction and possible severe asphyxia.
    In very rare cases, – swelling of the skin and mucous membranes (such as the face and throat ), a sudden drop in blood pressure and shock; increased sensitivity to sunlight and ultraviolet radiation (see “Cautions.”); hypersensitivity pneumonitis; vasculitis.
    In some cases: severe rash with blistering, such as Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell’s syndrome) and exudative erythema multiforme. General hypersensitivity reactions may sometimes be preceded by lighter skin reactions. The above-mentioned reaction may develop after the first dose in a few minutes or hours after administration.
    The action on the gastrointestinal tract and metabolism
    Common: nausea, diarrhea.
    Sometimes, loss of appetite, vomiting, abdominal pain, dyspepsia.
    Rare: bloody diarrhea which in very rare cases, it may be a sign of bowel inflammation and even pseudomembranous colitis (see “Special instructions”.).
    Very rare parabolan : drop in blood sugar levels (hypoglycemia), which has particular importance for patients with diabetes; possible signs of hypoglycemia. “ravenous” appetite, nervousness, sweating, tremor
    Experience with other quinolones suggests that they are capable of causing an exacerbation of porphyria (a very rare metabolic disease) in patients who are already suffering from the disease. Such an effect is not excluded the application tavanic drug.
    The action parabolan on the nervous system
    Sometimes, headache, dizziness, and / or numbness, drowsiness, sleep disturbances.
    Rare: depression, anxiety, psychotic reactions (eg, hallucinations), discomfort (eg, paresthesias in the hands), tremor, psychotic reactions such as hallucinations and depression ., an excited state, convulsions and confusion
    Very rare: visual and hearing impairment, disturbances of taste and smell sensitivity, reduction of tactile sensitivity.
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  • trenbolone hexahydrobenzylcarbonate

    Levofloxacin blocking  gyrase (topoisomerase II) and topoisomerase IV, and crosslinking gives supercoiling of  breaks, inhibit  synthesis, causes profound morphological changes in the cytoplasm, the cell wall and membranes.
    Levofloxacin trenbolone hexahydrobenzylcarbonate is active against most strains of microorganisms in conditions in vitro and in vivo.

    Aerobic gram-positive microorganisms: Corynebacterium urealiticum, Corynebacterium xerosis, Enterococcus faecium, Staphylococcus epidermidis  ( Methicillin-resistant), Staphylococcus haemolyticus methi-R
    Aerobic gram-negative microorganisms: Burkholderia cepacia, Campilobacter jejuni / coli
    anaerobic microorganisms: Bacteroides thetaiotaomicron, Bacteroides vulgatus, Bacteroides ovaius, Prevotella spp , Porphyromonas spp.
    By levofoloksatsnnu resistant :
    Aerobic gram-positive microorganisms: Corynebacterium jeikeium, Staphylococcus aureus methi- R, Staphylococcus coagulase-negative methi-R
    Aerobic Gram-negative microorganism: Alcaligenes xylosoxidans
    Other microorganisms: Mycobacterium avium.

    Levofloxacin is rapidly trenbolone hexahydrobenzylcarbonate and almost completely absorbed after oral administration. Food intake has little effect on the speed and completeness of removals. Bioavailability of 500 mg oral levofloxacin after is nearly 100%. After administration of a single 500 mg dose of levofloxacin is the maximum concentration of 5.2-6.9 g / ml, the maximum time – 1.3 hr, half-life -. 8.6 h.
    Relationship to plasma proteins – 30-40%. It penetrates the tissues and organs: lungs, bronchial mucosa, sputum, organs of the urogenital system, bone tissue, cerebrospinal fluid, the prostate gland, polymorphonuclear leukocytes, alveolar macrophages.
    In the liver, a small part of the oxidized and / or deacetylated. Report from the body mainly by the kidneys by glomerular filtration and tubular secretion. Following oral administration, approximately 87% of the dose is excreted in the urine unchanged within 48 hours. Less than 4% was found in feces for a period of 72 hours.

    Indications

     

    Therapy light to moderate bacterial infections susceptible to levofloxacin in adults.

    • acute sinusitis;
    • exacerbation of chronic bronchitis;
    • community-acquired pneumonia;
    • complicated urinary tract infections (including pyelonephritis);
    • uncomplicated urinary tract infections;
    • prostatitis;
    • infections of skin and soft tissues;
    • sentitsemiya / bacteremia associated with the above indications;
    • intra-abdominal infections;
    • for the integrated treatment of drug-resistant forms of tuberculosis.

    Contraindications

     

    • hypersensitivity trenbolone hexahydrobenzylcarbonate to levofloxacin or other quinolones;
    • epilepsy;
    • tendon injury during the earlier treatment of quinolones;
    • childhood and adolescence (18 years);
    • pregnancy;
    • lactation.
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  • parabolan side effects

    Tavanic must not be used to treat parabolan side effects children and adolescents because of the probability of destruction of the articular cartilage.
    In the treatment of elderly patients should be aware that patients in this group often have impaired renal function (see. Section “Dosing and administration”)
    for very severe pneumonia, caused by pneumococcus tavanic may not give the optimal therapeutic effect. Hospital infections caused by certain pathogens (P. aeruginosa), may require combination therapy.
    During treatment with Tavanic may develop seizures attack in patients with previous brain damage caused by, for example, stroke or severe injury. Seizure may be increased, and while the application fenbufena similar to him NSAIDs or theophylline (sm. “Interactions”).
    Despite the fact that the photosensitivity observed in the application of levofloxacin is very rare, in order to avoid her patients is not recommended to be subjected unnecessarily to strong sunlight or artificial ultraviolet light (eg, exposure to the sun in the highlands or the solarium).
    If you suspect pseudomembranous colitis should parabolan side effects immediately cancel tavanic and start appropriate treatment. In such cases, you can not use drugs that suppress intestinal motility.
    Rarely observed when using the drug tavanic tendinitis (especially inflammation of the Achilles tendon) may lead to tendon rupture. Elderly patients are more prone to tendonitis. Corticosteroid treatment ( “cortisone preparations”) are likely to increase the risk of tendon rupture. If you suspect tendonitis, stop treatment with Tavanic and start appropriate treatment of the affected tendon, for example, providing him rest state (see. “Contraindications” and “Side effects”).
    Patients with deficiency of glucose-6-phosphate dehydrogenase (an inherited metabolic disorder) fluoroquinolones can respond to the destruction of erythrocytes (hemolysis). In this regard, the treatment of such patients with levofloxacin should be carried out with great care.
    These side effects Tavanic drug like dizziness or numbness, drowsiness and visual disturbances (see. Also section “Side effects), can impair reactivity and ability to concentrate. this can be a risk in situations where these abilities are of special importance (eg while driving, during maintenance of machines and mechanisms, when working in an unstable position). in particular as parabolan side effects it concerns cases of drug interactions with alcohol.

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  • buy parabolan

    Sometimes buy parabolan increase in the number of eosinophils, a decrease in the number of white blood cells
    Rare: neutropenia, which may be accompanied by increased bleeding.
    Very rare: agranulocytosis and the development of severe infections (persistent or recurrent fever, sore throat and a persistent deterioration of health).
    In some cases: haemolytic anemia; pancytopenia.Other side effectsSometimes:. General weakness (asthenia)
    Very rarely. Fever, allergic pneumonitis
    Any antibiotic therapy can cause changes in the microflora (bacteria and fungi), which is normally present in humans. For this reason, it may happen enhanced reproduction of bacteria and fungi that are resistant to antibiotics are used (secondary infection and superinfection), which in rare cases may require additional treatment.

    Overdose

    The most important expected symptoms (signs) of erroneous overdosing tavanic occur at the level of the central nervous system (confusion, dizziness, impairment of consciousness and seizures seizures by type epipripadkov). In addition, it can be marked gastrointestinal symptoms (eg, nausea) and erosive lesions of the mucous membranes.
    The clinical and pharmacological studies conducted by the supra-therapeutic doses of levofloxacin was shown lengthening the interval.
    Treatment should be focused on presenting symptoms. Levofloxacin is not displayed by dialysis (hemodialysis, peritoneal dialysis and continuous peritoneal dialysis). Specific antidote (counteracting agent) does not exist. Error receiving one extra tablet buy parabolan of the drug will have no harmful effects.

    Interaction with other drugs

    There are reports of pronounced lowering the threshold of convulsive readiness, while the use of quinolones and substances that can, in turn, lower the cerebral seizure threshold. Equally, it also relates to the simultaneous use of quinolones and theophylline, fenbufena or similar to it nonsteroidal antiinflammatory drugs (for the treatment of rheumatic diseases).
    The drug tavanic expression weakened, while the use of sucralfate (means to protect the gastric mucosa). The same thing happens with the simultaneous use of magnesium-aluminum containing antacids or (drugs for the treatment of heartburn and gastralgia), as well as salts of iron (for the treatment of anemia). Tavanic should take no less than 2 hours before or 2 hours after the administration of these agents.With calcium carbonate interaction have been identified. Receiving corticosteroids increase the risk of tendon rupture.
    With the simultaneous use of buy parabolan antagonists should be monitored for blood coagulation system.
    Excretion (renal clearance) of levofloxacin slightly slowed down by the action of cimetidine and probenicid. It should be noted that this interaction is almost does not have any clinical significance. However, while the use of drugs such as cimetidine and probenicid blocking certain way of deducing (tubular secretion), treatment with levofloxacin should be performed with caution. This applies primarily to patients with reduced renal function.
    Levofloxacin slightly increases the half-life of cyclosporin.
    Receiving corticosteroids increase the risk of tendon rupture.

     

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